Podcast
The Age Reversal Project
Your front-row seat to the longevity frontier.
I sit down with scientists, founders, and pioneers exploring whether we can slow, repair, or reverse aspects of aging. We talk about the breakthroughs they’re pursuing, the questions they’re trying to answer, and what it could mean for our strength, independence, and years ahead.
Earlier episodes were published under The Optimized Woman.
Episode library
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Listen →September 14, 2026 · 1 hr 4 min · Dr. Shoma Datta-Thomas
Hormone Therapy, GLP-1s & Peptides for Women’s Longevity
Dr. Shoma Datta-Thomas joins me to discuss hormone therapy, testosterone, GLP-1s, and peptides, and the questions women are asking about health and longevity.
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Listen →August 19, 2026 · 22 min · Rabbit Hole #1
Can We Reverse Human Aging? Inside the $101M XPRIZE
What would meaningful age reversal look like? I explore XPRIZE Healthspan and its focus on muscle function, cognition, and immune resilience.
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Listen →July 15, 2026 · 51 min · Dr. Karen Mann
Microdosing GLP-1s: Can Less Actually Work Better?
Dr. Karen Mann discusses personalized GLP-1 dosing, food noise, and the role of behavior change in long-term weight management.
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Listen →March 4, 2026 · 55 min · Dr. Scott Sherr, MD
Methylene Blue for Brain Fog, Anxiety and Low Energy
Methylene blue is one of the most talked-about tools in biohacking for mitochondrial function, brain fog, and energy. The nuance is in dosing, quality, and context. In this episode, Dr. Scott…
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Listen →December 30, 2025 · 1 hr 13 min · Dr. Bill Campbell
Weight Loss Resistance in Midlife: What the Research Reveals I Dr. Bill Campbell, PhD
If you’re strength training, eating “clean,” and still gaining fat or losing muscle after 40, it’s not just willpower,it’s physiology. In this episode we break down what actually changes during…
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Listen →December 2, 2025 · 50 min · Dr. Amy Killen
Women’s Hormones & the Future of Longevity Medicine
This episode explores how women’s hormones, aging, regenerative therapies, and technology are shaping the next era of longevity medicine. Dr. Amy Killen shares her evolution from ER doctor to…
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Listen →November 11, 2025 · 48 min · Carol Covino
A Female Bodybuilder’s Guide to Muscle & Metabolism Over 50 I Carol Covino
Discover how to build lean muscle, balance hormones, and reignite metabolism after 50. In this episode, you’ll learn the science behind muscle as a metabolic organ, how to train smarter (not harder)…
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Listen →October 14, 2025 · 1 hr 8 min · Jim Donnelly
How AI Is Revolutionizing Longevity Medicine
Discover how precision diagnostics, regenerative therapies, and AI are redefining the future of personalized healthcare. In this episode, you’ll learn how data-driven medicine, early disease…
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Listen →October 7, 2025 · 1 hr 0 min · Faraz Khan
Hormonal Imbalances & Hair Thinning: What Every Woman Should Know
Hair thinning, gray hair, and hair loss don’t have to be inevitable! In this episode, we explore the science of hair health and dive into the root causes of these issues, including hormonal imbalances…
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Listen →August 26, 2025 · 1 hr 3 min · Shalin Shah
Why Testosterone Levels Dropped 50% Worldwide
Testosterone levels have dropped by nearly 50% over the past 40 years, creating ripple effects in metabolism, mood, fertility, and longevity. In this episode, you’ll learn why hormones are declining…
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Listen →August 19, 2025 · 43 min
Closing the Gender Gap in Women’s Health Research I Katie Moore & Mackenzie De Jesus
Women’s health research has historically overlooked critical differences in female biology. In this episode, Katie Moore and Dr. Mackenzie De Jesus join me to uncover the persistent gender gap in…
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Listen →August 12, 2025 · 1 hr 6 min · Dr. Bryce Appelbaum
How to Improve Vision & Brain Performance
Your vision is more than just seeing clearly. It's a direct reflection of your brain function and overall health. In this episode, we explore the groundbreaking field of neuro-optometry and how vision…
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Listen →August 5, 2025 · 1 hr 5 min · Ryan Monahan
Reverse Hashimoto’s and Autoimmunity Naturally
If you're struggling with fatigue, weight gain, brain fog, or unexplained symptoms despite “normal” labs, this episode will help you uncover what’s really going on. We explore how thyroid…
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Listen →July 22, 2025 · 1 hr 4 min · Lindsay O’Neill
Inside the Biohacking Routine of a Mom and CEO I Lindsay O’Neill
What happens when a tech executive and mom of three uses biohacking to heal herself and her child from autoimmune dysfunction, chronic UTIs, and fatigue? Lindsay O’Neill shares her daily routine, the…
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Listen →July 15, 2025 · 1 hr 9 min · Joel Greene
Gut Health: The Missing Key to Sustainable Weight Loss
If you're stuck in the cycle of restrictive dieting and rebound weight gain, your gut may be the root cause. In this eye-opening episode, Joel Greene shares how gut diversity, immune signaling, and…
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Listen →July 8, 2025 · 42 min · Kristin Weitzel
Unlocking Your Inner Strength: The Right Way to Do Cold Therapy for Women
Cold therapy can be a powerful tool for fat loss, metabolic health, stress resilience, and recovery, but women need a different approach than men. In this episode, we break down the best way to use…
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Listen →July 1, 2025 · 46 min · Mollie Eastman
Sleep Optimization & Circadian Health Explained
If you're exhausted but can't sleep, stuck in a cycle of sleeping pills, or struggling to fix your sleep despite trying everything. This episode is for you. Sleep expert Molly Eastman reveals the…
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Listen →June 24, 2025 · 1 hr 6 min
Real Talk on Perimenopause, Hormones, and HRT I Dr. Salome Masghati
This episode reveals the hidden risks of hormonal birth control, how it alters your gut, mood, and long-term health, and why most OB/GYNs are missing the mark on hormone therapy. Learn how estrogen…
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Listen →June 17, 2025 · 54 min · DR. DOUG LUCAS 🎙️
Osteoporosis Prevention & Hormone Replacement Therapy I Dr. Doug Lucas
Osteoporosis isn’t just a concern for older women,it often starts much earlier than you think. Bone health is deeply connected to hormones, metabolism, and nutrition, and the right approach can not…
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Listen →June 12, 2025 · 57 min · Nat Niddam
A Holistic Take on GLP-1s for Weight Management
Struggling to lose weight despite a healthy lifestyle? In this episode, holistic nutritionist Nat Niddam joins us to uncover the science and strategy behind GLP-1 weight-loss peptides. We explore…
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Listen →June 10, 2025 · 1 hr 2 min · Dr. Jennifer Haley
How to Reverse Premature Aging: The Interplay of Nutrition & Dermatology
Your skin isn’t just about looking good,it reflects your inner health. In this episode, we explore how cold therapy, breathwork, hormones, metabolism, fat loss, recovery, and stress resilience all…
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Listen →June 5, 2025 · 54 min
Unlocking the Secrets to a Fulfilling Sex Life I Dr. Molly Maloof
In this episode, Dr. Molly Maloof returns for an eye-opening conversation on the intersections of intimacy, relationships, and longevity. Discover why connection and intimacy are foundational to…
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Listen →June 3, 2025 · 54 min · Dr. Eric Balcavage
Understanding the Cell Danger Response in Thyroid Health
Still tired, gaining weight, and burning out-even on thyroid meds? You're not broken. In this episode, we're joined by Dr. Eric Balcavage to explore why conventional thyroid treatments often fail and…
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Listen →May 29, 2025 · 1 hr 1 min · Tucker Goodrich
Heart Health & The Shocking Truth About Seed Oils
The conversation around fats and heart health has been distorted for decades. In this episode, we uncover the surprising truths about saturated fats, seed oils, and their actual impact on heart…
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Listen →May 27, 2025 · 48 min · Sarah Kennedy🎙️
How GLP-1 Impacts Fat Loss & Hunger in Women I Sarah Kennedy
In this episode, we dive into groundbreaking research on GLP-1s and other hunger hormones and how a clinically studied plant compound is helping women reduce cravings, improve appetite control, and…
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Listen →May 12, 2025 · 1 hr 2 min · Lisa Pitel-Killah
Minerals, Electrolytes & Energy Explained
Struggling with chronic fatigue, hormonal imbalances, or finding the right balance for peak performance? Join Lisa Pitel-Killah, world champion kettlebell athlete and expert in Hair Tissue Mineral…